Yegorova D. The interaction of dinuclear clusters rhenium(III) compounds with phospholipids and higher fatty acids during microcapsule formation

Reactions of cluster rhenium compounds with phospholipids, higher fatty acids and with the nuclear basis, the obtaining liposomes and solid microcapsules of cluster rhenium compounds. Definition of characteristic features of the interaction of dinuclear cluster rhenium compounds with phospholipids and higher fatty acids during liposomes and solid microcapsules formation and in reactions with the nuclear basis. IR-, electronic and chromomass spectroscopy, proton magnetic resonance, X-ray structural and elemental analysis, electronic microscopy. Determinate ability of compounds with quadruple bond Rhenium- Rhenium to react with phospholipids, higher fatty acids, and with the nuclear basis, widens and extends the knowledge about multiple bonds in clusters of transition metal . It gives significant material for theory of structure and chemical bond. Developed liposome form techniques on a base of dinuclear cluster rhenium compounds and solid microcapsules of higher dispersity techniques let to use efficiently dinuclear cluster rhenium compounds as biologically active systems. Liposome forms and solid microcapsules of dinuclear cluster rhenium compounds were first obtained and fully investigated. It was shown, that coordination of phosphatidylcholine and higher fatty acids to cluster centre Re26+ occurs during liposome forms and microcapsules formation. This lets to increase of stability and biological activity of Rhenium(III) clusters. The data obtained from PhD thesis are recommended for use in coordination with a chemistry course and a course of chemistry of rare elements in institutions of higher education of chemical and chemical-technological directions.