Narovchenko T. The optimization of posttraumatic vitreous hemorrhage treatment

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0410U004703

Applicant for

Specialization

  • 14.01.18 - Очні хвороби

29-10-2010

Specialized Academic Board

Д 41.556.01

State Institution "The Filatov Institute of Eye Disease and Tissue Therapy of NAMS of Ukraine"

Essay

Object: posttraumatic vitreous hemorrhage. Purpose: optimization of posttraumatic vitreous hemorrhage treatment. Methods: visual acuity testing, biomicroscopy (slit lamp "Opton"), ophtalmoscopy (ophthalmoscope "Keeler"), ultrasound examination (apparatus Cine Scine "Quantel Medical" company), cytological and immunochemical methods of peripheral blood and vitreous examination, statistical. For the first time, it was established that autoimmune and non-specific immune reactions were activated in case of fibrous organization of posttraumatic vitreous hemorrhage. The scientific data were supplemented concerning: the low level of the organism sensibilization to the vitreous antigens (not more than 10%) in resorption of posttraumatic vitreous hemorrhage after closed globe injury; the activation of specific immune reactions in posttraumatic injuries of posterior segment of the eye (CD25, CD38 and CD54 in peripheral blood increased 2,4 times); and more pronounced activation of CD16 (increased by 35%) in decompensation of secondary posttraumatic glaucoma compared with its subcompensation. For the first time, it was proposed the method of diagnosing the posttraumatic vitreous hemorrhage fibrous organization, the method of prediction the posttraumatic vitreous hemorrhage resorption, the method of preventing the retinal detachment after vitrectomy for posttraumatic vitreous hemorrhage. The results of this work were implemented at the State Institution "The Filatov Institute of Eye Diseases and Tissue Therapy of Academy of Medical Sciences of Ukraine", and at the Kharkov National Medical University. The sphere of use - medicine, ophthalmology.

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