Masoudnaseri M. New method efficacy of secondary maculodystrophy treatment, occured after rhegmatogenous retinal detachment

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0410U005210

Applicant for

Specialization

  • 14.01.18 - Очні хвороби

25-06-2010

Specialized Academic Board

Д 41.556.01

State Institution "The Filatov Institute of Eye Disease and Tissue Therapy of NAMS of Ukraine"

Essay

Object - rhegmatogenous retinal detachment. Purpose - to increase the efficacy of treatment of patients with rhegmatogenous retinal detachment. Methods - visometry, ophthalmoscopy, optical coherent tomography; biochemical: investigation of enzymes activity of lactatedehydrogenase, pyruvatedehydrogenase, succinatedehydrogenase, cytohromoxidase, level of ADF and ATF. Devices - optical coherent tomograph. Firstly it was showen, that the development of secondary maculodystrophy due to influence of high intensivity light, manifested by destabilisation of retina's lysosomes membranes and disturbanses of oxide-redox processes in the retina. It was found a new data, that application of oxybral stabilizes retina's lysosomes membranes, increases the steadiness of retina to hypoxia due to normalization of activity of oxide-redox enzymes and increasing of ATF level on 35%. The new method of rhegmatogenous retinal detachment treatment have been worked out. The results are adopted at the Filatov Institute. The sphere of application: medicine, ophthalmology.

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