Ehorova S. The immunoreactivity of patients with ulcerative colitis with varying degrees of intestinal disbiosis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0410U005571

Applicant for

Specialization

  • 03.00.09 - Імунологія

28-09-2010

Specialized Academic Board

Д 26.001.14

Taras Shevchenko National University of Kyiv

Essay

It was found out that patients with ulcerative colitis have decline of functional activity of neutrophils to Escherichia coli is the factors of risk of progress of disbiosis. It is shown that the level of IL-8 and TNF- а in the blood is the expressed tension of immunity and prognostication of motion of disease. Frequency of detection and titers of autoantibodies to the intestine were higher at patients with subcompensated disbiosis, and autoantibodies against neutrophil granulocytes - at patients with decompensation disbiosis.

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