Shishkova K. Clinical characteristics and treatment of rheumatoid arthritis combined with hypertension

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0410U006129

Thesis Registration Form

0410U006129.pdf

Applicant for

Specialization

  • 14.01.02 - Внутрішні хвороби

29-10-2010

Specialized Academic Board

Д29.600.01

Essay

This thesis summarizes the results of a study conducted on 122 patients with rheuma-toid arthritis (RA), out of which 82 patients had hypertension syndrome. The study estab-lished common pathogenic mechanisms, including the presence of chronic inflammation, endothelial dysfunction, which manifests itself primarily as result of a disruption of nitric oxide (NO) bioavailability and increase of its systemic synthesis in patients with сomor-bid pathology. Under the influence of combined AHT, the patients noted improvement as a reduction in breathlessness, disappearance of headaches, dizziness, cardialgia, disap-pearance of the symptoms of malfunctioning cardiac activity, improvement of sleep, and reduced irritability. Also, under the influence of intended AHT, there was an increase in para-sympathetic influence on heart rate, lowering blood pressure, reduction in markers of inflammatory process, and reduction of stable metabolites of NO in the blood.

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Files

aref.doc

diss--АНАЛІЗ ТА УЗАГАЛЬНЕННЯ РЕЗУЛЬТАТІВ ДОСЛІДЖЕННЯ.doc

diss--ВИСНОВКИ.doc

diss--ВСТУП.doc

diss--ЗМІСТ.doc

diss--ПЕРЕЛІК УМОВНИХ СКОРОЧЕНЬ.doc

diss--ПРАКТИЧНІ РЕКОМЕНДАЦІЇ.doc

diss--РОЗДІЛ 1.doc

diss--РОЗДІЛ 2.doc

diss--РОЗДІЛ 3.doc

diss--РОЗДІЛ 4.doc

diss--РОЗДІЛ 5.doc

diss--РОЗДІЛ 6.doc

diss--РОЗДІЛ 7.doc

diss--СПИСОК ВИКОРИСТАНОЇ ЛІТЕРАТУРИ.doc

diss--Титул.doc

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