Kovalchyk A. Optimization of breast cancer surgical treatment by the way of biological tissue welding usage

Object of research: biological tissue-welding living tissues in experiment and at treatment of breast cancer into practice. The Research objective: to improve a surgical method of treatment of a breast cancer by application biological tissue-welding tissues. Methods: the general clinical; the densithometrical; the histological; the biochemical; the statistical analysis. Scientific novelty: for the first time basic possibility of increase of efficiency of surgical treatment of a breast cancer by application biological tissue-welding soft tissues is proved, morphological changes in hypodermic cellular tissue under the influence of biological tissue-welding in experiment are studied; influence biological tissue-welding on biochemical changes in whey of blood and a drainage liquid at patients of a breast cancer is defined; Dependence of early and late complications of mastectomy from concentration of the transforming factor of growth in whey of blood of patients, and also metaboliques of oxide nitrogen, malonic dialdehyde and carbonic groups of fibers in a drainage liquid is established; economic benefit of application biological tissue-welding is calculated at surgical treatment of a mammary gland cancer. Results: application biological tissue-welding accelerates rehabilitation of patients of a breast cancer after surgical treatment; the effective way of diagnostics of fibrosis hypodermic cellular tissue by means of ultrasonic densimetry is developed, allowing to predict development of complications of surgical treatment of breast cancer and in due time to appoint preventive treatment. It is introduced in clinical practice of surgical departments of the Donetsk Regional Antitumoral center, the Vinnitsa regional clinical oncological clinic and the Chernovitsky regional clinical oncological clinic, in educational process of department of radiodiagnostics, radiotherapy and oncology Vinnitsa national medical University nemed after M. I. Pirogov. Branch - medicine (oncology).