Turova L. The role of microelements in pathogenesis and treatment of children with IUGR.

The advanced study deals with the research of one of the urgent problems of modern paediatrics, which is the increasing of treatment efficiency of newborns with intrauterine growth retardation. The levels of microelements (iron, zinc, lead) in blood serum and red blood cells of women who gave birth to children with intrauterine growth retardation and blood serum, red blood cells and urine of newborns during neonatal period were investigated. Iron deficit in serum and red blood cells and zinc deficit in blood serum and high level of lead in serum and disbalance of these microelements in pregnant women result in deficit and disbalance of microelements in the organism of a fetus and a newborn. Iron and zink deficit in serum and red blood cells was found out in newborns on the bachground of lead overload in serum and red blood cells and the considerable loss of iron with urine at the low level of lead elimination.The results of cross-correlation analysis testify the influence of microelements on intrauterine growth retardation pathogenesis. The algorithm of prognostication of intrautherine growth retardation is developed according to iron, zinc and lead levelsin serum and red blood cells of a pregnant. The expediency and efficiency of microelement medicine usage for treatment of children with the intrauterine growth retardation was grounded.