Kostenko O. Improvement of laboratory diagnostics and prevention of intrahospital rotavirus infection of newborns.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U002177

Applicant for

Specialization

  • 03.00.06 - Вірусологія

21-04-2011

Specialized Academic Board

Д 26.003.01

Essay

Object of research of -ce inwardly hospital infection, improvement of laboratory diagnostics and prophylaxis of mouth of viral infections in new-born. Purpose: to develop the methodical ground of ways of improvement of specific laboratory diagnostics and prophylaxis of in-hospital rotavirusnoy infection is scientific in the new-born in maternity hospitals and specialized neonatologichnikh separations of lechebno-profilakticheskikh establishments of m. of Kiev. Methods are applied for high-quality and Methods are applied for high-quality and kolichestvennogoopredeleniya rotavirusiv and their antigens in new-born, their mothers and at a medical personnel, in the cultures of cages at creation of experimental model; serum - for determination of specific antibodies in new-born, their mothers and at a medical personnel; sanitary virologic is sampling with ob''ektiv of environment, from hands, methods of concentration of viruses in tests, indication of viruses in washings off with ob''ektiv of environment of obstetric obstetric and neonatologichnikh permanent establishments; bacteriological - for quantitative and high-quality composition of microflora of different biotopiv new-born and ob''ektiv of environment of obstetric and neonatologichnikh permanent establishments; citomorfologichni - for the estimation of virulicidnoy action of dezinfektantiv; mathematical analysis and statistical processing of data. Scientific novelty of the got results. The virologic looking is first carried out after forming and in-hospital distribution TEAR among Frequency of infecting of rotavirusami is set new-born in obstetric permanent establishments, in new-born with perinatal'noy pathology in the separations of pathology of new-born and nursing of nedonoshenikh children. Found out a direct middle degree cross-correlation zv''yazok frequencies of infecting of children of RV with duration of their stay in the conditions of permanent establishment. Developed and offered to the practical guard of zdorov''ya: methodical recommendations of "Applications of rapid tests are in laboratory diagnostics of infectious diseases" (MOZ of Ukraine ratified an order ?467 from 23.09.2004r. "O claim of methodical recommendations in relation to application of rapid tests for checking of blood for infectious diseases, registration form and instruction in relation to its filling"); order MOZ of Ukraine ?158 from 24.03.2006 Degree of introduction consists in that were drawn on research results in-process 2-oh medical establishments of guard of zdrovyaUkraine "158 from 24.03.2006 Degree of introduction consists in that were drawn on research results in-process 2-oh medical establishments of guard of zdrovya, that is confirmed the proper acts.

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