Kozynkevych G. Clinical and metabolic features in children with recurrent nondiabetic ketonemia with underlying uratic diathesis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U002444

Thesis Registration Form

0411U002444.pdf

Applicant for

Specialization

  • 14.01.10 - Педіатрія

05-04-2011

Specialized Academic Board

Д 26.003.04

Bogomolets National Medical University, Ministry of Health of Ukraine

Essay

The thesis is dedicated to the study of recurrent nondiabetic ketonemia (primary acetonemia) in children with underlying uratic diathesis and consists in increasing of efficiency of diagnostics and treatment of purine metabolism disorder. Specific methods of observation such as serum lipid composition, nitrogen metabolism end products (urea, urinary acid, kreatinine), nitric oxide system activity (nitric oxide synthases, nitrite and nitrate ions) and free amino acid profile have been used. Complex therapy including metabolic drug Tiotriazoline has been accompanied with positive clinical dynamics, remission period prolongation and has provided metabolic care with ketogenesis and hyperuricemy significant decreasing.

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Files

Aref.doc

dis.doc

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