Bugera O. Clinical and pathogenetic study of correction of mineral metabolism disorders in children with diffuse endemic goiter on the background of concurrent disease

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U003061

Applicant for

Specialization

  • 14.01.10 - Педіатрія

23-03-2011

Specialized Academic Board

К 58.601.02

Essay

Dissertation focuses on children's health body, growing under conditions of iodine deficiency on the one hand, the accelerated pace of development and available to other concurrent disease, which is quite possible to be able to destabilize the mechanisms of bone mineralization and their morpho-functional characteristics.Shown that the most often in children with diffuse endemic goiter degree turns and pathology of the digestive and skeletal systems. Combined pathology results in destabilization of the mineral homeostasis, an imbalance in the exchange of calcium, phosphorus. Violated hormonoprodukuyucha function of the thyroid and pituitary (TSH level above the optimum in 37.70% of the examined children). In 61.65 % of girls and 16.44 % of boys were found osteopenic changes of different severity.Pathogenetically expedience and the scheme and correct disorders of mineral metabolism in children with diffuse endemic goiter І power law of soputststvuyuschey pathology of mineral-vitamin complexes, which contains in its structure including vitamins A, E, C, minerals iodine, selenium, calcium, phosphorus, magnesium and etc.. And if found lower bone mineral density - in combination with calcium preparations. In the dynamics of tracked improvement of children's health, the stabilization level of thyroid hormones, metabolic bone macro indicators.

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