Tkachuk N. Clinical and experimental study on the use mouthwash containing phospholipase A2 inhibitor, in treatment of chronic recurrent aphthous stomatitis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U003514

Applicant for

Specialization

  • 14.01.22 - Стоматологія

16-05-2011

Specialized Academic Board

Д 41.563.01

State Establishment «Institute of Stomatology and Maxillofacial Surgery National Academy of Medical Sciences of Ukraine"

Essay

Dissertation is devoted to substantiation and assessment of the effectiveness of use in treatment of patients with chronic recurrent aphthous stomatitis inhibitor of phospholipase A2 (chlorogenic acid) on the basis of studying the role of phospholipase A2 in the pathogenesis of stomatitis. A "phospholipase" model stomatitis was developed. A compounding health care mouthwash with the introduction of the inhibitor of phospholipase A2 was developed. Shown that patients with chronic recurrent aphthous stomatitis use in treatment developed by mouthwash significantly accelerates clinical recovery, less time of aphtha epithelization and reduces number of relapses.

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