Tomina O. Clinical significance of heart rate variability, types of orthostatic reaction and circadian profile of blood pressure in hypertension, comorbid with peptic ulcer disease

The object of the research is manifestations of hypertension, comorbid with peptic ulcer disease. The goal is to determinate a clinical significance of heart rate variability, the types of orthostatic reaction and circadian profile of blood pressure in control efficiency of hypertension, comorbid with peptic ulcer; methods are- clinical, laboratory, instrumental, morphological and statistical; a novelty of this research is that there were fixed specific features of spectral heart rate variability, defined the frequency of types of orthostatic reaction and circadian profile in patients with hypertension comorbid with peptic ulcer disease, evaluated the efficiency of control of hypertension comorbid with peptic ulcer disease, at the stages of antihypertensive therapy, including the types oforthostatic reaction and circadian profile of blood pressure. The observed data were introduced into practice of the polyclinic № 6 of Kharkov, DLPZ "Central klіnіchna lіkarnya Ukrzaliznytsya", multidisciplinary hospital № 18 of Kharkov, in the pedagogic process of the Department of Internal Medicine Medical Faculty of Kharkov National University V.N.Karazin and the Department of Therapy of Nephrology and the Kharkiv Medical Academy of Postgraduate Education Ministry of Ukraine.