Lutsyk M. Cytomorphological characteristics of NK/Ly lymphoma cells and their surface carbohydrate determinants in the investigation of effectivity of potential antitumor preparations.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U004625

Applicant for

Specialization

  • 14.03.09 - Гістологія, цитологія, ембріологія

30-09-2011

Specialized Academic Board

Д 20.601.02

Ivano-Frankivsk national medical university

Essay

Cytological criteria for evaluation of the effect of chemotherapeutics upon tumor cells in vivo are proposed which includes the analysis of cell dimension distribution in population; morphometric computer-linked analysis of smears stained by azure-eosin, bromophenol blue, hematoxylin and neutral red. Indexes for quantitation of cell damage are defined. Sapogenins of Great celandine and Spurge olive exhibited cytotoxicity towards NK/Ly cells, yet therapeutic effect was nonsignificant.

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