Ushenina L. Clinical-pathogenetic features of chronic hepatitis C in patients with metabolic risk factors

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U005469

Applicant for

Specialization

  • 14.01.13 - Інфекційні хвороби

05-07-2011

Specialized Academic Board

Д 26.614.01

State Institution "The L.V. Gromashevsky Institute of epidemiology and infectious diseases of NAMS” of Ukraine"

Essay

In dissertation work complex investigation of clinical-biochemical and immune-endocrinal indices, morphological changes in liver was done in patients with chronic hepatitis C and metabolic risk factors. It was found that patients with metabolic risk factors have higher cytolisis of hepatocytes, higher leptin, insulin and TNF-? serum levels than in patients without these factors. Influence of immune-endocrine parameters and metabolic risk factors to liver fibrosis and steatosis was uncovered in research work.

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