Pershyna K. Dynamics of serum levels of transforming growth factor-beta1 in therapy of patients with essential hypertension and diabetes mellitus type 2.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U000271

Thesis Registration Form

0412U000271.pdf

Applicant for

Specialization

  • 14.01.02 - Внутрішні хвороби

24-01-2012

Specialized Academic Board

Д 26.613.06

Shupyk National Medical Academy of Postgraduate Education

Essay

This dissertation examines the dynamical pattern of serum levels of transforming growth factor-beta1 (TGF-beta1) in patients with essential hypertension (EH) with or without diabetes mellitus (DM) type 2; the connections between the level of this factor and peculiarities of development of the EH and DM type 2. The patients with EH and DM type 2 had significantly higher levels of this factor when compared to the patients with EH only. It is determined that the antihypertensive therapy with perindopril combined with nebivolol and indapamid when used with atorvastatin and metformin therapy most efficiently lowers the level of TGF-beta1.

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Files

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