Umanska I. The new method efficacy of initial stage age-related macular degeneration treatment

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U001413

Applicant for

Specialization

  • 14.01.18 - Очні хвороби

10-02-2012

Specialized Academic Board

Д 41.556.01

State Institution "The Filatov Institute of Eye Disease and Tissue Therapy of NAMS of Ukraine"

Essay

Object: The initial stage of age macular degeneration. Purpose: To increase the effectiveness of the treatment of patients with initial stage of macular degeneration by the age of a new method of drug therapy based on the correction of the enzymatic antioxidant system of the retina preparation lipoflavon. Methods: obscheoftalmologicheskie, optical coherence tomography, the phenomenon of Haidinger, multifocal electroretinography, light sensitivity, fluorescent angiography, biochemistry, statistics, slit lamp, ophthalmoscope, the device Stratus OCT, semi adaptometer, makulotester polarization MTP-2, setting Retiscan, the fundus camera. Extended data that the effect of high intensity light leads to disruption in the antioxidant defense system of the retina. New data on the mechanisms of the protective action of lipoflavona in the development of degenerative process in the retina. Expanded view of the state of antiradical enzyme systems in blood of patients with early stage AMD. For the first time found that systemic administration of lipoflavona helps to normalize the activity of major antioxidant enzymes. A method for treatment of early stages of AMD, which is the application of 10 daily intravenous injections lipoflavona followed by instillation of the drug 5-6 times a day for 2 months, 2 times a year. A new method of treatment introduced in the Institute of Filatov, the Military Health Clinical Center of the Southern Region, Odessa, Lugansk oblast center of eye diseases. Scope of application - medicine, ophthalmology.

Files

Similar theses