Sysun L. Тranscranial triplex Doppler in diagnostics of acute ischemic stroke.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U002051

Applicant for

Specialization

  • 14.01.23 - Променева діагностика та променева терапія

15-03-2012

Specialized Academic Board

Д 64.609.01

The Kharkiv Medical Academy of Postgraduate Education, Ministry of Health of Ukraine

Essay

On the ground of observation of representative groups of patients with acute ischemic cerebral circulation disorders the topical for radiodiagnosis and neurology scientifi c task concerning the improvement of the studied pathology diagnosis quality has been solved, effi ciency of ultrasonic examination (transcranial Doppler) has been grounded at the stage of initial evaluation of patients. Technique for transcra nial Doppler (TCD) in triplex mode has been improved. TCD triplex Doppler signs have been systematized for acute hemispheric ischemic stroke and transient ischemic attack, their dif ferential diagnostic criteria have ben defi ned. TCD diagnostic effi ciency in triplex mode has been established while comparing with MRI and CT fi ndings. In the diagnosis of acute hemispheric ischemic stroke TDC sensitivity compared with MRI fi ndings at peak systolic blood fl ow velocity in MCA <50 cm/s on the affected side the following levels were obtained: sensitivity 98.0%, specifi city - 75,0 % accuracy - 96.2 %; at peak systolic blood fl ow velocity > 150 cm/s on the affected side, respectively, they were 90.5, 80, 88.5 %. In the diagnosis of acute hemispheric ischemic stroke at the value of peak systolic blood fl ow velocity <50 cm/s on the affected side compared to the CT findings - sensitivity was 93.8%, specifi city - 80.0% accuracy - 90.5%. The nature of blood fl ow disorders in cerebral veins at acute hemispheric ischemic stroke has been determined. The interrelation between arterial and venous hemodynamics changes has been established.

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