Shpak S. Possibilities of 64-slice computed tomography in differential diagnosis of malignant and benign liver lesions

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U002278

Applicant for

Specialization

  • 14.01.23 - Променева діагностика та променева терапія

18-04-2012

Specialized Academic Board

Д 11.600.06

Essay

Object of research - liver tumors. A research objective:increase of efficiency of differential diagnostics of liver tumors on the basis of application of contrast multiphase research on 64-sections a computer tomograph. Research methods - clinical, instrumental, laboratory, morphological, statistical processing of results. Novelty: for the first time the technique of multiphase contrast research adapted to 64- sections to a computer tomograph, with specific features of haemodynamics of patients which influences quality of visualisation of tumours and vascular architectonics is developed. The algorithm of differential diagnostics of liver tumors according to contrast multiphase research on 64- sections a computer tomograph is offered. Results:sensitivity of the 64- sections КТ at malignant and benign tumours of a liver makes 100 % (ВІ 90,5-100 %), specificity at malignant tumours - 95,8 (ВІ 88,2-99,6 %), at benign tumours - 95,3 % (ВІ 87,6-99,3 %). The developed algorithm of differential diagnostics of liver tumors assists timely planning of medical actions. It is introduced in practice of the of department of computer and MR-image Donetsk clinic, Medical centre "Langeron" of Odessa, in the Cardiological clinic of of Lugansk, and also at Institute of urgent and regenerative surgery of V.K.Gusaka of Donetsk. Results of work are used in educational process of Donetsk national medical university named after M.Gorky. A field of application: medicine (radiodiagnostics).

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