Kovalchuk T. Optimization of monitoring of juvenile rheumatoid arthtritis in children of all ages.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U004186

Applicant for

Specialization

  • 14.01.10 - Педіатрія

28-08-2012

Specialized Academic Board

К 76.600.02

Essay

Object - monitoring of current of juvenile rheumatoid arthtritis at children of different age; the purpose - to improve algorithm of monitoring of juvenile rheumatoid arthtritis at children of different age on the basis of a complex estimation of activity of process, functional infringements, a degree of quality of a life for definition of efficiency basic and antibasic; methods - clinical, laboratory - instrumental, immunologycal, social - psychological, statistical; results - it is proved, that index DAS is the most informative parameter of activity of disease at children's age; it is created ukrainianlanguage the version of questionnaire CHAQ, is proved its reliability, sensitivity, is relative, estimations minimal clinical-significant changes in a state of health of children; the estimation of quality of a life of children with juvenile rheumatoid arthtritis with the help of a questionnaire is made, is proved, that sufficient psychometric characteristics of this questionnaire allow to establish interrelation of infringements physical and psychoemotinal health at juvenile rheumatoid arthtritis; definition of index DAS is established, that, a level of functional infringements on questionnaire CHAQ and qualities of a life on questionnaire CHQ are informative enough at an estimation efficiency basic and antybasic therapies; the algorithm of monitoring of course juvenile rheumatoid arthtritis is proved.

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