Kirichenko I. Laboratory diagnostic and frequency of mycoplasma community acquired pneumonia in combination with herpes virus infection in military personnel

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U005373

Applicant for

Specialization

  • 03.00.07 - Мікробіологія

25-06-2012

Specialized Academic Board

Д 64.618.01

State Institution "I.Mechnikov Institute of Microbiology and Immunology National Academy of Medical Sciences of Ukraine"

Essay

Object of investigation: inflammation infectious processes in the lungs of the military personnel. Methods of investigation: clinic-Xray, cytoscopic, bacterioscopic, bacteriological, serum, molecular-biological, mathematical statistics. Equipment: spectrophotometer, "Biolam" microscope, thermostat, autoclave, dry-heat cabinet, pH-meter. The resuts of the investigation sufficiently clarified the interpretation of prevalence of associated forms of infections in the patients with community-acquired pneumonia in the form of active or persistent subclinical form. For the first time the role of microbe association represented by taxomanically different pathogens of the Mycoplasmataceae type and Herpesviridae type was clarified for the patients with community-acquired pneumonia third clinical group. The necessity of applying complex clinical and bacteriological-virus laboratory diagnostics for augmentation of etiological verification of community-acquired pneumonia was discussed. A new diagnostic algorithm for combined mycoplasma community-acquired pneumonia in combination with herpes virus infection in the third clinical group patients was developed. The laboratory diagnostics of for mixed infections caused by mycoplasma herpes virus association was improved and a quantity method of persistent herpes virus infection activity diagnostics was recommended. Practical application: 2 Ukrainian patents, 2 methodological recommendations, practical application in the Military medical institutions of the Ukrainian MD, practical application in the process of teaching at microbiological, immunological and virology departments , therapeutic departments of the medical higher educational establishments ofUkrain. Sphere of application: medicine (therapy, pulmonology , infectious diseases ).

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