Malik N. Optimization of treatmentof chronic generalized periodontitis in the acute stage.

The dissertation is dedicated to improving the quality of treatment of patients with pathology of periodontal tissues, namely CGP I and II degree in acute stage. The study of the microbial content of periodontal pockets in patients with CGP I and II degree in the acute stage showed that the presence of all five pathogens we have defined in the study population is not required. Developed and tested a method of complex treatment of patients with CGP I and II degree based on immunological and molecular biological studies. A comparative evaluation of clinical efficiency combination of ciprofloxacin and ornidazole on the results of PCR, indicators of hygiene index according to Fedorov, Volodkina, Schiller - Pisarev Svrakova iodine value, the depth of periodontal pockets, the degree of bleeding, the degree of mobility of the teeth, periodontal index for Russel, on PMA Parma, which testifies to a decrease of the inflammatory process and the achievement of sustained remission at 6 and 12 months. Analysis of data from laboratory and clinical studies have proved the feasibility and effectiveness of the proposed method for the treatment of CGP I and II degrees in acute drug combinations of ciprofloxacin and ornidazole in comparison with the treatment of lincomycin hydrochloride. The analysis of short-and long-term outcomes of patients with CGP I and II degree in the acute stage showed high clinical effectiveness of the proposed method in clinical dentistry.