Machogan V. Clinical and experimental study of treatment of patients with generalized periodontitis with synbiotic medications

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0413U000504

Applicant for

Specialization

  • 14.01.22 - Стоматологія

21-01-2013

Specialized Academic Board

Д 41.563.01

State Establishment «Institute of Stomatology and Maxillofacial Surgery National Academy of Medical Sciences of Ukraine"

Essay

With the developed model of experimental periodontitis in rats found morphological changes such as: the epithelial lamina mucosa gingiva with increased сeratinization and disceratozis phenomena, in the granular layer in the lamina propria revealed edema, spasm of arterioles, in periodontal observed swelling of ground substance, in the alveolar bone occurred activation of osteoclasts with local destruction of bone tissue. The complex of preventive measures using synbiotic medications "Baktulin" in the treatment of patients with generalized periodontitis contributed to a significant reduction of exacerbations, reduce indices PMA and PI.

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