Kuzmenko A. Microbiological, cytological and immunological criteria for diagnosis of inflammation caused by Gardnerella vaginalis

The thesis is devoted to the development of adequate diagnostic scheme gardnerellosis. Classic gardnerellosis characterized in 81.6% of cases, the lack of complications of mixed infection and inflammation of the genitals. In immunological studies of patients with gardnerellosis established decline in B-lymphocytes in women aged from 21 to 30 years, observed latent immunological suppression of T-system of immunity. By leukocyte reaction with 3-s degree course gardnerellosis: 1-and-moderate, 2 - pronounced, and 3- pronounced. Activity of succinate dehydrogenase can be used as a marker of initial changes microbiocenosis of vagina. Found that biotypes 1, 2 and 3 were positive on the test lipase that helps break down triglycerides to free fatty acids - which are nutrients and contributes to the further reproduction gardnerella. When gardnerellosis installed decreasing concentration ?-ketoglutorate, causing inhibition of amino acid metabolism and may influence the reproductive function of women.