Zyn A. Free radical processes and iontransport systems status of loach embryos under the sodium hypochlorite influence

The thesis is devoted to the study of free radical and membrane associated processes in loach (Misgurnus fossilis L.) embryos under the action of sodium hypochlorite. Found that sodium hypochlorite leads to intensification of lipids and proteins peroxidation, disbalanced antioxidant defense system functions and inhibition of iontransport enzymes (Na+, K+- та Ca2+, Mg2+-ATPase). Found that stage of 16 blastomeres of early development are most sensitive to sodium hypochlorite at all concentrations. According to ANOVA sodium hypochlorite has a significant share of influence on the activity of Na+, K+- та Ca2+, Mg2+-ATPase and catalase, while changing the content of carbonyl groups of redox-modified proteins, as well as the change of antioxidant defense system enzyme activity (superoxide dismutase, glutatіonperoxydase, glutatіontransferase) reliable overwhelming share of influence comes at a time of embryonic development.