Chernishov A. Mechanisms of evolution, diagnostics and prediction central lumbar spinal stenosis (clinical-experimental research).

Object - central stenosis of the lumbar spinal canal in patients with lumbar osteochondrosis and in experimental animals. Objective: To improve the diagnosis and prognosis of central lumbar spinal stenosis based on experimental and clinical and radiological study of the mechanisms of its development. Methods: clinical, radiographic , including computed tomography quantitative determination of the degree of degenerative changes in the lumbar segments of the spinal canal and the size of its walls, Doppler inferior vena cava, experimental simulation constrictive deformity of the lumbar spine in laboratory animals. For the first time experimentally demonstrated probability increased volume content of the spinal canal to the development of endo-, epinevralnyh and vascular changes in laboratory animals under conditions modeling reduction of hyperplasia channel through its walls . First set of correlation changes in the size of the central region of the vertebral canal, the severity of degenerative changes in posterior lumbar support complex motor segments and individual parameters spinal- pelvic balance. For the first time correlation of severity of clinical symptoms of lumbar central spinal stenosis , chronic venous insufficiency in the basin of the inferior vena cava and other related diseases. First developed a conceptual model of the pathogenesis of lumbar spinal stenosis central New evidence on the relationship between the severity of neurological disorders, impaired hemodynamics in the basin of the inferior vena cava and intercurrent diseases will avoid the mistakes that lead to unsatisfactory results in solving problems of diagnostic , prognostic and therapeutic nature . Computing table using clinical and radiological signs will significantly increase the quality of recognition of the central lumbar spinal stenosis and promptly initiate a reasonable pathogenetic therapy. Computational prognostic tables allow a sufficient accuracy perebachyty clinical course of central lumbar spinal stenosis and to determine a rational treatment strategy that will significantly improve its performance, and finally, to improve the quality of life in this category hvoryh.Rezultaty research introduced into clinical practice SI "Sytenko Institute of Spine and Joint Pathology National Academy of Medical Sciences of Ukraine" and the educational process of the department of traumatology and orthopedics Kharkiv Medical Academy of Postgraduate Education of Health of Ukraine and Kharkiv National Medical University, Ministry of Health of Ukraine .