Chystyakova S. Visual analyzer's structural and functional changes and efficacy of "dry eye" syndrome combined treatment in women of reproductive age at pathological hyperprolactinemia.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0414U003569

Thesis Registration Form

0414U003569.pdf

Applicant for

Chystyakova Svitlana Volоdymyrivna

Specialization

14.01.18 - Очні хвороби

Date of defense

20-06-2014

Specialized Academic Board

Д 41.556.01

State Institution "The Filatov Institute of Eye Disease and Tissue Therapy of NAMS of Ukraine"

Essay

Object: syndrome of "dry eye" and pathological hyperprolactinemia (HPRl). Purpose: to identify and study the features of structural and functional abnormalities of eyeball and visual analyzer, features of "dry eye" syndrome and optimize methods for early diagnosis and disorder's treatment in women of reproductive age with pathological HPRl. Methods: clinical, ophthalmic, immuno-biochemical, statistics; Stratus OCT-3000, Humphrey HFA-740, slit lamp. There were refined scientific data on the structural-functional changes of visual analyzer in women of reproductive age with pathological HPRl. For the first time found that pathological HPRl is a risk factor for "dry eye" syndrome occurrence and testosterone deficiency determines its degree. Scientific data were expanded on the characteristics of "dry eye" syndrome pathogenesis in women of childbearing age with pathological HPRl. In women with pathological HPRl were revealed features, identified structural and functional abnormalities of the visual analyzer, which have importance in early diagnostics and dynamic monitoring of the hypothalamic-pituitary area. Combined method of "dry eye" syndrome prevention and treatment by use of local and topical instillation of tear volume and topic nonsteroidal anti-inflammatory drugs on the background correction of hormonal imbalance inhibitors of prolactin secretion was introduced into clinical practice in 9 medical institutions of Ukraine. Results of work are being used in lectures in SI "Crimea State Medical University named after S.I. Georgievskij ." Sphere of use - medicine, ophthalmology.

Thesis supervisor

Ivanova Nanuli Viktorivna

Official opponents

Недзвецька Ольга Володимирівна
Дрожжина Галина Іванівна

Files

aref.doc

dis.doc

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