Semesiuk N. Disseminated tumor cells and the level of cytokines in bone marrow and peripheral blood of breast cancer patients as a complex of biomarkers of tumor recurrence risk

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U003040

Thesis Registration Form

0415U003040.pdf

Applicant for

Specialization

  • 14.01.07 - Онкологія

08-04-2015

Specialized Academic Board

Д 26.155.01

R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology National Academy of Sciences of Ukraine

Essay

The thesis is dedicated to investigation of more informative prognostic markers of tumor recurrence by identifying disseminated tumor cells (DTC) in bone marrow (BM) with simultaneous determination of cytokine status in breast cancer (BC) patients. The level of proinflammatory cytokines (TNF, IL-1 beta, IL-6) and growth factors (CSF-1, TGF- beta 1, VEGF, IFN) were estimated, analyzed their relationship with the presence of DTC in BM, the risk of relapse and an estimation predictive value of these indicators.

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Files

aref.doc.doc

dis.doc.doc

dis.doc.doc

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