Kukushkina M. Sentinel lymphadenectomy in the combined treatment of patients with skin melanoma of extremities and trunk

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U003507

Thesis Registration Form

0415U003507.pdf

Applicant for

Specialization

  • 14.01.07 - Онкологія

27-05-2015

Specialized Academic Board

Д 26.560.01

National Cancer Institute

Essay

The thesis is dedicated to improving the treatment effectiveness of patients with skin melanoma through the introduction sentinel lymphadenectomy. The object of study were 309 patients with melanoma of extremities and trunk thicker than 1.0 mm by Breslow in the absence of clinical signs of metastases in regional lymph nodes.The melanoma thickness 1,01-2,0 mm is associated with a statistically significant decrease of metastases in SLN (p=0,0001), the thickness more than 4,0 mm - with an increase (p=0,005). At the threshold thickness of primary tumor 2,8 mm likelihood of metastasis in SLN increases 6,2 times compared with lower rates (OR = 6,2; p=0,0001).

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Files

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