Yasinskyi R. Combined therapy of patients with co-infection of TB/HIV taking into account risk factors with progression of TB

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U004638

Thesis Registration Form

0415U004638.pdf

Applicant for

Yasinskyi Roman Mykolayovych

Specialization

14.01.26 - Фтизіатрія

Date of defense

21-09-2015

Specialized Academic Board

Д 26.552.01

State organization “National Institute of Phthisiology and Pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine”

Essay

The object of the study: co-infection tuberculosis/HIV (TB/HIV); aim - to increase the effectiveness of treatment of patients with first diagnosed and relapse of TB with HIV co-infection by using of additional differentiated pathogenetic treatment on the basis of biochemical features, indicated risk factors with progression of disease; methods: clinical, radiological, microbiological, laboratory, immunological and statistics; novelty: first time established, that patients with co-infected TB/HIV have more severe proinflammatory changes and an imbalance in the antioxidant defense system in the blood. The risk factors with progression and 3 variants of disease state were determined. It justified the usage of additional differentiated combined therapy with aprotinin and glutamyl-cysteinyl-glycine disodium for patients with 2 and 3 variants of disease state Field of application - medicine.

Thesis supervisor

Shalmin Oleksandr Samuilovich

Official opponents

Мельник Василь Павлович
Процюк Раду Георгійович

Files

aref.doc

diss.doc

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