Keremet M. The scientific bases of synthesis technology products of oxidation of 4-aminotoluene ozone in the liquid phase

The object of study - technology of producing 4-aminobenzyl alcohol (4-ABS) and 4-aminobenzaldehyde (4-ABA). The aim is to develop the scientific bases of technology of synthesis of 4-ABS and 4-ABA catalytic oxidation of 4-aminotoluene (4-AT) ozone in the liquid phase. The study kinetics and mechanism of reactions of ozone with 4-AT and 4-acetamidotoluene (4-AAT) in a solution of acetic anhydride. Studying the process of liquid-phase catalytic oxidation of 4-AT ozone to 4-ABS and 4-ABA, in the presence of transition metal compounds. Development of preparative methods of synthesis 4-ABS and 4-ABA and the fundamental technological scheme of production. Research methods - GC, spectrophotometry, NMR and IR spectroscopy, colorimetric. Developed new preparative methods of selective low-temperature oxidation of 4-AT ozone for 4-ABS and 4-ABA. They are characterized by high yields and the quality of end products and can serve as a basis for further improvement of the oxidation processing reagents. A process flow diagram for preparing 4-ABS and 4-ABA. The effectiveness of the proposed method of synthesis of 4-ABS was confirmed by the scientific and industrial state of emergency scheme "Avist" (Kiev).