Gavryschuk A. Substantiation of comprehensive prevention of basic stomatological diseases for the workers of metallurgical industry

The workers of metallurgical production was observed 100% prevalence of dental caries in its high intensity , superlinear growth of the index KPUz with duration of their work and 96,5 % prevalence of periodontal disease , disorders of detoxification genes GSTM1 and bone metabolism. In an experiment on rats in the modeling of harmful production factors tested developed therapeutic complex , allowed to normalize the disturbed biochemical parameters of the gums , bone , blood serum , to reduce atrophy of the alveolar bone. Caries preventive effectiveness of developed complex for 2 years of observations in the growth of caries among workers averaged in the group was 25.6 % and in the group with high caries intensity - 32.1% , parodont protective efficiency by Parma index was 57 %, and the index Myulleman - 50%. This normalized biochemical and biophysical indicators of oral liquid, buccal epithelial cells and the functional state of gums microcapillary bed.