Shyyka O. Annulated nitrogen-containing heterocycles based on functionalized 2- and 3-aminothiophenes

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U005794

Applicant for

Specialization

  • 02.00.03 - Органічна хімія

19-10-2015

Specialized Academic Board

Д.35.052.01

Essay

Dissertation is devoted to the research and development of new methods for the synthesis of annulated nitrogen-containing thiophene heterocycles based on functionalized 2- and 3-aminothiophenes. New anionic domino-reactions of thiophenes with 1,3-dipolar substituent were investigated. Convenient one-pot method for synthesis of hardly availible substituted thieno[2,3-d]pyrimidinones and thieno[3,2-d]pyrimidinones was developed. A number of readily available and not widely described heterocyclic systems with thiophene core were obtained.

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