Bezrodna O. Peculiarities of HCV-related liver cirrhosis, depending on its stage.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U005898

Applicant for

Specialization

  • 14.01.13 - Інфекційні хвороби

30-10-2015

Specialized Academic Board

Д 26.614.01

State Institution "The L.V. Gromashevsky Institute of epidemiology and infectious diseases of NAMS” of Ukraine"

Essay

The study involved 139 patients with chronic hepatitis C, of whom 104 patients had HCV-associated liver cirrhosis. The complex clinical-laboratory and instrumental analysis of the peculiarities of HCV-associated liver cirrhosis, depending on its stage was performed. Predictive value of biochemical markers (De Ritis ratio, index APRI) for the differentiation between classes of HCV-associated liver cirrhosis was established. Peculiarities of virological and biochemical responses during standard antiviral treatment in patients with compensated HCV-associated cirrhosis depending on the virus genotype and presence of metabolic syndrome were evaluated.

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