Deev B. Chickenpox in children: peculiarities of pathogenesis, clinics, treatment

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U005977

Thesis Registration Form

0415U005977.pdf

Applicant for

Deev Bladimir Vyacheslavovich

Specialization

14.01.13 - Інфекційні хвороби

Date of defense

30-10-2015

Specialized Academic Board

Д 26.614.01

State Institution "The L.V. Gromashevsky Institute of epidemiology and infectious diseases of NAMS” of Ukraine"

Essay

A retrospective analysis of 533 medical records of children with chickenpox, aged from 2 weeks to 18 years, who were at the clinic of the department of pediatric infectious diseases in the years 2007-2014 and found that 97,2% of patients the disease occurs in a typical, 76,9% - moderate form, 2,8% - an atypical form, 45,2% - with complications. The cytokines were measured in blood serum in 135 patients with chickenpox and marked increase in the level ІFN-alpha -2,5, IFN-beta - 11 times, IL-4 -5 times, IL-1beta -2,9 times, IL-6 - 7 times, reduced IL-2 by 2,2 fold, TNF-alpha -3 times (p<0,05). In the dynamics of the detected imbalance increased. Improved therapy with moderate forms.

Thesis supervisor

Kramarev Sergey Aleksandrovich

Official opponents

Руденко Антоніна Олексіївна
Усачова Олена Віталіївна

Files

arref.doc.doc

disser.doc.doc

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