Chornobai M. The efficacy of photodynamic therapy in treatment of bacterial keratitis, considering changes in acid-base balance of the tear film

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U006590

Applicant for

Specialization

  • 14.01.18 - Очні хвороби

27-11-2015

Specialized Academic Board

Д.41.556.01

Essay

Object of study - bacterial keratitis. Objective: To increase the effectiveness of treatment of bacterial keratitis of various etiology by improving methods of antimicrobial photodynamic therapy taking into account the differential diagnostic value changes in acid-base balance of the tear film on the basis of fluorescence keratography. Methods: history, biomicroscopy, functional tests, microbiological, bacteriological, laboratory and statistics; slit lamp, DVR, microscope. Established the effectiveness of PDT in bacterial keratitis, as evidenced by a complete regression of inflammation 10 days and normalization of pH 7 days. It was established that the use of PDT in bacterial keratitis causes normalization of tear pH (7 days) in contrast to antibiotic therapy (14 days), the rehabilitation of content conjunctiva 5 vs 8 days. A method of non-invasive diagnosis of the bacterial keratitis, which is to determine the color content conjunctival cavity and the affected cornea. The results introduced in clinical practice SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine", Central Polyclinic MIA of Ukraine, private enterprise" and Assistant Professor ", Lviv National Medical University named Danylo Galickogo. Sphere of use - medicine, ophthalmology.

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