Shatynska T. Clinical features and mechanisms of anthracycline cardiomyopathy in children with acute leukemia, their prevention and treatment.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0416U004159

Applicant for

Specialization

  • 14.01.10 - Педіатрія

29-09-2016

Specialized Academic Board

К 20.601.03

Ivano-Frankivsk national medical university

Essay

According to the results of comprehensive study of clinical signs, peroxidation system condition, energy supply and markers of myocardial damage and heart failure in children with anthracycline cardiomyopathy with the background of the acute leukemia, and considering the results of experimental study of the cardioprotection mechanisms’ influence on the rats’ myocardium under the conditions of simulated toxic cardiomyopathy, it was proven the effectiveness of levokarnitine supplementation of the protocol treatment of such children. Grown - medicine.

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