Kliukovskii D. Trifluoromethylaminocycloalkanes and their derivatives

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0416U005575

Applicant for

Specialization

  • 02.00.03 - Органічна хімія

08-12-2016

Specialized Academic Board

Д 26.217.01

Institute of Organic Chemistry NAS of Ukraine

Essay

The simple and effective synthetic methods of fluorinated cycloalkylamines have been developed. On the base of them first representatives of N-cyclopropylimidoylchlorides, iminophpsphonates and trifluoromethylated isocyanates have been syntesized. The obtained amines and isocyanates were used for synthesis of new derivatives of neonicotinoids which showed the high insecticidal activity and the fluorinated analogues of antidiabetic drug Glibenclamide.

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