Boichuk V. The role of intestinal hormones and pepsinogens in the development of gastroesophageal reflux disease combined with endemic goiter in conditions of iodine deficiency and differentiated approaches to its treatment

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0416U005731

Thesis Registration Form

0416U005731.pdf

Applicant for

Boichuk Vira Bohdanivna

Specialization

14.01.02 - Внутрішні хвороби

Date of defense

25-11-2016

Specialized Academic Board

Д 20.601.01

Ivano-Frankivsk national medical university

Essay

We have investigated the features of clinical signs and character of changes of the mucous membrane of the lower third of the esophagus in 80 patients with gastroesophageal reflux disease and 40 - its combination with endemic goiter. Multidirectional changes in levels of gastrin-17 and cholecystokinin - pankreozymin and pepsinogens I, II were established in patients. It was accompanied by different types of gastrooesophageal refluxes, dysmotility of gastroesophageal zone and thyroid dysfunction. This has led to the use such combined therapy of drugs as proton pump inhibitor, prokinetic, ursodeoxycholic acid and iodine. Branch - medicine.

Thesis supervisor

Mishchuk Vasyl Grygorovych

Official opponents

Федів Олександр Іванович
Осьодло Галина Василівна

Files

aref.doc

dis.doc

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