Zombor K. Pathogenic substantiation of differentiated prevention dental caries in children of city Uzhgorod with different mineral composition of drinking water

It is shown that in children of 6-7 years in the city of Uzhgorod in permanent occlusion which use water from artesian wells with high concentrations of nitrate and strontium chloride, carious lesions of teeth is higher intensity in 2,8 times, while the prevalence in 2.12 times than similar indicators among children using river Uzh water. Experimentally in rats at drinking water sources of the city Uzhgorod was substantiated its differentiated use of health-care complex. In two years of observation in children, according to sources artesian well and river Uzh was obtained caries-preventive effect in 41.1% and 48.5%, decrease in oral liquid of PMA% index in 1.31 and 1.37 times, increase level of calcium by 100% and 34%, normalization activity of catalase, lysozyme, urease, reduction the extent of oral cavity dysbiosis. Also in major groups of children 2 times reduced pH fluctuations in oral liquid, approached the average norm ratio of amplitudes electrophoretic shift Plasmol and nuclei of buccal epithelium, increased acid resistance of tooth enamel and efficiency of the defense of hyaluronic acid - hyaluronidase gums.