Otchych O. Prooxidant-antioxidant balance for the combined use of chemo-lasero-ozone therapy in the blood of patients with pulmonary tuberculosis.

Dissertation is devoted to the investigation of features of influence of standardized chemotherapy, frequency modulated and unmodulated He-Ne intravenous laser irradiation of blood, ozonized saline solution with varying concentrations of ozone and their combinations on prooxidant-antioxidant balance, level molecules of middle mass in the blood of patients with first diagnosed destructive pulmonary tuberculosis with bacterial. It was established that the development of tuberculosis is characterised by a significant increase of the activity of oxidative processes, decreased activity of enzymes of antioxidant system (SOD, catalase) increased levels of ceruloplasmin, compared with healthy donors. The realization of effects of frequency modulation of laser radiation depends on the character of and depth of the violations output values of studied parameters. The performed two-factor dispersive and cluster analysis of combined influence of ozonized saline and laser in violation POL/AOS balance in patients blood with lung tuberculosis under chemotherapy confirmed the effectiveness of these modes combined with use of chemo-laser-ozonetherapy.