Roborchuk S. Peculiarities of the progression mechanisms of the chronic kidneys disease in patients with rheumatoid arthritis depending upon the methods of anti-inflammatory therapy

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0417U004153

Thesis Registration Form

0417U004153.pdf

Applicant for

Roborchuk Stanislav Volodymyrovych

Specialization

14.01.02 - Внутрішні хвороби

Date of defense

17-10-2017

Specialized Academic Board

Д 58.601.02

Essay

In the dissertation on the basis of a survey of 138 patients the indexes of lipid peroxidation and antioxidant defense, morphofunctional state of erythrocytes, lipid profiles, changes in pro- and anti-inflammatory blood and urine cytokines in patients with rheumatoid arthritis and chronic renal disease were studied. Mechanisms of progression and mutual burdening of the renal chronic disease in patients with rheumatoid arthritis have been studied. The diagnostic value of the monocyte chemoattractant protein-1 of blood and urine as a marker for the mutual burdening of the comorbidity of rheumatoid arthritis and chronic renal disease is proved. The ways of optimization of complex anti-inflammatory therapy of patients with rheumatoid arthritis combined with comorbid flow of chronic disease of kidneys are determined.

Thesis supervisor

Zub Lilia Oleksiivna

Official opponents

Яцишин Роман Іванович
Дудар Ірина Олексіївна

Files

aref.doc

dis.doc

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