Ulasevych L. Features of the clinic, treatment and prevention of the caries of temporary teeth in children with the adenoids' hypertrophy.

Dissertation work is devoted to increasing the effectiveness of prevention and treatment of caries in deciduous teeth in children with adenoids hypertrophy by developing preventive measures based on clinical and laboratory studies of pathogenic mechanisms of caries. It has been established that in children 3-5 years with adenoid hypertrophy, the prevalence and intensity of caries of temporary teeth is observed in comparison with practically healthy children, which occurs on the background of unsatisfactory oral hygiene, decrease in salivation rate, shift in the acidic side of the hydrogen index of oral liquid, increase its viscosity, decrease of the mineralizing potential and acidity of the enamel with increase of the index of the enamel resistance test (р<0,05). The statistically significant correlation relations of the studied indicators with the development of caries of temporary teeth were established according to the correlation coefficients of Pearson, Spirman and Kendall. It was found that in children of 3-5 years old with adenoid hypertrophy, there is a significant reduction in calcium and inorganic phosphorus content in the oral liquid, lysozyme activity and increase of urease activity, presence of clinical subcompensated oral cavity dysbiosis, decrease in catalase activity and increase in the content of TBA-reactants, reduction antioxidant-prooxidant index. As a result of application within 1,5 years of the proposed treatment and prophylaxis complex in children with adenoids hypertrophy, it was possible to improve all the studied parameters and get the caries preventive effect at 63,6%.