The dissertation is devoted to the urgent problem of orthopedic dentistry - the problem of reducing the risk of infection of dentists, dental technicians, support staff of dental clinics, as well as other patients by decontamination of impressions. The analysis of modern trends in the development of medicine and orthopedic stomatology in particular testifies to the urgent need for the development and implementation of effective methods of prevention, treatment and rehabilitation in the practice of providing medical care. At the same time, in the clinical practice of orthopedic dentistry, the quality of dental materials that are used at the clinical and laboratory stages of the manufacturing of the proper orthopedic constructions is a primary importance. The main disadvantage of domestic alginate imprint materials is the lack of decontamination effect. The decontamination of the prints is carried out with using physical methods, or, for the most part, chemicals are used. But these methods can lead to deformation of the imprints, which in turn is reflected in the accuracy of reproduction of prosthetic lids on plaster models. In addition, these methods are quite labor-intensive, require the use of additional equipment and much time spent on disinfection. In this regard, we have developed an improved alginate imprint material with peroxide K-30, which has decontamination properties. In order to substantiate its formulation, we studied the physical, mechanical and technological properties of different formulations of alginate repellent compositions, and their comparative rating was made. Based on the results of these studies, the formulation of the improved alginate repellent material was approved, which was subject to further researches to determine its properties. The toxicological rating of the improved alginate imprint material. was performed to determine the possibilities of clinical usage of the proposed material. The researches were made to determine the physical and mechanical properties of the new material. The obtained data of physical and mechanical researches testify that the improved alginate imprint material in its properties fully meets the requirements of ISO 1563-2011. Comparative analysis showed that the new material according to the main indicators is not worse than the similar material (p <0,01). It has been established that the material developed by us ((149,5 ± 2,5) c) is statistically (p <0,05) less than 13,0% of the time of structuring than analogue ((169,3 ± 6,2) c) It also discovered ((1,79 ± 0,2) %) significantly (p <0,05) less by 5,3%, compared to the analogue ((1,9 ± 0,2) %) the deformation index at compression. The compressive strength index was the same for both materials ((0.66 ± 0.03) N / mm2) (p <0.05). The dimensional accuracy of gypsum models, when using new material, was provided at 99.3% of linear dimensions. As a result of a microbiological study, it was found that the degree of contamination of the prints is due to the kind of alginate imprint that was applied. The use of advanced alginate imprint material significantly reduces in 30% the level of contamination of the prints compared with the analogue. In this case, the use of the material developed by us provides decontamination of prints from the main types of microbiota and its minimum possible presence on plaster models. Excluding the procedure of soaking the prints in aqueous solutions of antiseptics, which can affect their dimensional accuracy and deform the surface, allows you to produce more precise and qualitative models of prosthetic lodges.