Sergiyenko Y. Surgical Treatment of Hypervascularized Meningiomas with Preoperative Embolization of Tumor Vessels

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0418U000877

Applicant for

Specialization

  • 14.01.05 - Нейрохірургія

10-07-2018

Specialized Academic Board

Д 26.557.01

The State institution "Romodanov neurosurgery institute, National academy of medical sciences of Ukraine"

Essay

The research goal was to improve the results of surgical treatment of patients with hypervascularized meningiomas through preoperative embolization of vasculature. The materials for this research are the results of clinical, instrumental and hystological observation of 103 patients with hypervascularized meningiomas who were examined and treated in the Department of neurosurgery of KZOZ OKL CEMD MK (Region Clinical Hospital, Emergency and Disaster Medical Care Center Municipal Enterprise) and the Department of neurosurgery of Railway KHKL (Kharkiv Clinical Hospital) No. 1 of the Unit of the Health Care Center of the State Administration of Railway Transport of Ukraine, PAT (public joint-stock company) "Ukrzaliznytsia" during the period from 2006 to 2016. The age of patients ranged from 19 to 69 years, women accounted for 59 (57,3%), men - 44 (42,7%). Patients involved in our research had predominantly basal localization meningiomas - 43 (41,7%) cases; there were also cases of convexital (35 cases, equal to 33,9% of patients), parassagital (22 cases, equal to 21,5% of patients) and subtentorial (3 cases, equal to 2,9% of patients) meningiomas. The most hypervascularized meningiomas were vascularized from one side of the external carotid artery pool - 53 (51,5%) cases, both from the external carotid artery and the internal carotid artery pools - 27 (26,2%) meningiomas, or from two sides of the external carotid artery pool - 15 (14,6%) meningiomas. Рatients were divided in groups. The I group consisted of 43 (41,7%) patients. It included patients who underwent preoperative endovascular embolization of tumor vasculature. For a more detailed study of results of treatment, the I group patients were divided in subgroups depending on the features of angioarchitectonics and the used embolic agent. The II group consisted of 60 (58,2%) patients who underwent surgical treatment following traditional methods with use of microsurgical techniques. Based on analysis of patients with hypervascularized meningiomas we developed scheme of application of differentiated endovascular treatment in patients with hypervascularized meningiomas. This allowed to improve the the surgical radicalization of hypervascularized meningiomas, to minimize intraoperative blood loss; contributed to reducing the number of relapses and continued growth of hypervascularized meningiomas and the prolongation of the non-recurring period while maintaining the quality of life of patients.

Files

Similar theses