Zaderei N. Microbiological substantiantion of the use of antiseptic drugs with decamethoxine® at suppurative diseases with staphylococcal etiology

Object – reference and clinical strains of Staphylococcus and other opportunistic pathogens that cause inflammatory diseases; aim – to develop a microbiological substantiation of the use of antiseptic drugs with decametoxin® for the treatment and prevention of purulent-inflammatory diseases of Staphylococcal etiology; methods – microbiological, morphological, biochemical, the study of the sensitivity of Staphylococci to antiseptics and antibiotics, the antimicrobial activity of antiseptic drugs under adverse conditions, the formation of resistance to antiseptics in microorganisms, mathematical and statistical; results – there was determined sensitivity to antibiotics, antiseptic preparations of Staphylococci isolated from patients with purulent-inflammatory diseases; a significant dissemination of antibiotic-resistant strains of S.aureus, isolated in the bacteriological laboratory of the Department of Microbiology, Virology and Immunology of the VNMU. M.I. Pirogov has been revealed; аs a result of the study of antiseptics and antibiotics, modern concepts characterizing the profile and width of the spectrum of antimicrobial action on museum and clinical strains of Staphylococcus and other conditionally pathogenic microorganisms that cause inflammatory diseases have been expanded and supplemented; the influence of adverse factors on the sensitivity of Staphylococcal strains to drugs was substantiated; a microbiological substantiation has been done for the feasibility and viability of using the drugs Decamethoxin®, Decasan®, and Horosten® for the prevention and treatment of Staphylococcal inflammatory diseases; the effect of antiseptic agents Decamethoxin®, Decasan®, Horosten®, and gentamicin on the adhesive properties of Staphylococci, the formation of resistant variants of Staphylococci has been investigated; branch – medicine.