Odud M. Clinical and laboratory grounds for reasonable choice of base materials for partial removable laminar prostheses in patients with denture defects

The dissertation is devoted to improvement of orthopedic treatment efficacy in patients with denture defects by substantiation of reasonable choice of base materials for partial removable laminar prosthesis (PRLP) on the basis of clinical and laboratory studies. Patients having partial denture defects with no correction (37 individuals), those wearing acrylic-based and thermoplastic-based PRLP during one year period (27 and 28 persons, respectively) were studied. Long-term results of orthopedic treatment of patients were analyzed by the data of clinical, biophysical, cytometric, cytologic and sociologic studies. Ineffective results of prosthetic treatment of partial adentia using acrylic-based PRLP were established in 25% of patients. Though patients with thermoplastic-based PRLP demonstrated some worsening in study indices after 6 months of observation, normalization or even significant improvement in treatment results was revealed after one year of using those dental appliances. In case of ineffective use of acrylic-based PRLP, indications for repeated prosthetic treatment using thermoplastic bases were developed, including evaluation of oral mucosa clinical status of patients, apoptosis indices and proliferative potential of buccal epithelial cells in DNA-cytometry, changes in biological medium of the oral cavity and balanced number of flat epithelial cells in cytograms as well as negative influence on different spheres of quality of life according to OHIP-14 questionnaire. Treatment efficacy of repeated orthopedic treatment with thermoplastic-based PRLP was 85.7%.