Bati V. Biological properties of lactobaсteria, promising for the creation of special prognostic purpose food products

Microbiological analysis of selected traditional fermented foods and beverages of vegetable origin of the Black Sea region countries at various stages of fermentation was carried out. The biological properties of isolated from them probiotical strains of microorganisms have been identified and studied, further selection of cultures and edible plants rich in biologically active components, which are able to selectively inhibit the growth of conditionally pathogenic representatives of the intestinal microbiota and stimulate commensal species of microorganisms have been carried out. For the first time, the spectra of the inhibitory and stimulating effects of about 25 different plant food components were investigated. Synergistic interaction of selected isolated probiotic microorganisms and plant components is shown. Based on the obtained data, samples of functional special prognostic purpose food products were developed. On in vivo experiments the influence of selected microorganisms and plant components on intestinal microbiota, lipid metabolism was investigated and their immunomodulatory effect was established. In this work the principles of creating functional foods based on plant components and original strains of lactobacilli for their prognostic and personalized use to prevent the occurrence of non-communication diseases (NCP), including obesity, through targeted correction of microbial intestinal cenosis of the macroorganism, and in turn lipid profile and immune status were proposed for the first time. The pro- and antimicrobial activity of the components of these products is the basis for the design of diets based on ethnic foods, taking into account the unique recipes of their preparation. Isolated microorganisms L. paracasei ІМВ В-7483, L. casei ІМВ В-7412, L. plantarum ІМВ В-7414 и L. plantarum KR-1 are perspective in manufacture of fermented foods products, and simply as a basis of pro- or synbiotic biopreparations.