Tokarchuk T. Biochemical processes in the piglet organism during the period of weaning and under the action of vitamin E and citrates Zn, Fe and Ge.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0420U101662

Applicant for

Specialization

  • 03.00.04 - Біохімія

06-10-2020

Specialized Academic Board

К 35.368.01

Institute of Animal Biology of NAAS

Essay

The dissertation is devoted to the experimental substantiation of the stasis factor of weaning along with the application of vitamin E and citrates of trace elements Zn, Fe and Ge during this period of life of pigs. The features of exchange of proteins, lipids and the state of the system of antioxidant protection for the use of vitamin E and citrates of trace elements Zn, Fe and Ge are shown at the time of weaning. In the thesis on the experimental data basis, the effectiveness of the usage of vitamin E and citrates Zn, Fe and Ge for pigs during their early weaning from sows was established. The parameters of the antioxidant status, protein, lipid metabolism, the content of lipid peroxidation products and hematological indices in the pigs organism were determined for their early weaning from sows and the vitamin E usage (α-tocopherol) and citrates Zn, Fe and Ge. It has been proved that drinking and injecting the tested drugs stimulates anabolic processes and contributes increasing the body weight of piglets. It has been experimentally established that the activity of superoxide dismutase and catalase in the serum of blood for 28th day of vitamin E and the maintenance of a complex of citrates Zn, Fe and Ge in a dose of 2,5 sm3/10 kg body weight and the 35th day of piglets' life significantly decreased by 21,5 and 14,4 % and 12,2 and 11,2 %, in conformity. The research results showed that for drinking of vitamin E and maintaining 2,5 sm3/10 kg body weight of the complex of citrates the content of lipid hydroperoxides in pigs’ blood serum of the experimental group decreased by 28 and 35 days of life with according to control, in conformity, by 15,6 and 12,7 %. The difference was probabilistic. In the pigs’ experimental group, a tendency was found to decrease the content of diene conjugates and TBA-active By results of researches it is established, that at various doses usage of a complex of citrates of microcells against a background of additional vitaminization with vitamin E the maintenance of hemoglobin in blood of pigs from research groups raises. Thus, keeping 2,5 sm3/10 kg body weight of the complex of citrates Zn, Fe and Ge leads to an increase of the hemoglobin content in blood of animals by 35,7 % on the 35th day of life relative to control. It was revealed that in these very piglets in the blood number of erythrocytes significantly increases. It is not established in blood from animals from the research groups likely increase or decrease in leucocytes count.

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