Olijnykova S. Influence jf intense L-thyroxine replacement therapy in combination withhhh the calcium antagonist (cordafen) jn functional characteristics jf cardiovascular systen diseased by hypothyroidism

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0499U000238

Applicant for

Specialization

  • 14.01.14 - Ендокринологія

02-02-1999

Specialized Academic Board

Д 26.558.01

STATE INSTITUTE "V.P. KOMISSARENKO INSTITUTE OF ENDOCRINOLOGY AND METABOLISM OF THE NATIONAL ACADEMY OF MEDICAL SCIENCE OF UKRAINE"

Essay

Тhe functional condition of the cardiovascular system of patients suffering from primary hyrothyroidism has been invesigated.The goal of investigaation is to study the influence produced by the intensive substitution therapy, which is based on the use L-tryroxine (L-T) in combination with the calcium antagonist(cordafenum) ,in the functional status of the cardiovascular system of patients with primary hypothyroidism.The clinical. biochemical and radioimmunological methods were used ie such devical as theograph, electrocardiograph were empioyed The functional condion of the cardiovascular system in case of alarm and spontaneous hypothyroisis has been established For the first time it was suggested to use the calcium antagonist (cjrdafen) at the intial stage of intensive substiution therapy by L-T to reduce the terms of restoration jf the functional status of the cardiovascular system of patients sulfering from primary hypothyroidism The mesods of investigation and cornection of cardiovascular sustem i n case of hypothyroidism are being introduced at the endocrinology departmens The feid of application is endocrinology and cardiology

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