Gendeleka G. Mechanisms of secondary sulfonylamide resistance development in non-insulin-dependent diabetics and methods of its correction.

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0501U000422

Thesis Registration Form

0501U000422.pdf

Applicant for

Specialization

  • 14.01.14 - Ендокринологія

04-12-2001

Specialized Academic Board

Д 26.558.01

STATE INSTITUTE "V.P. KOMISSARENKO INSTITUTE OF ENDOCRINOLOGY AND METABOLISM OF THE NATIONAL ACADEMY OF MEDICAL SCIENCE OF UKRAINE"

Essay

The dissertation is devoted to the study of mechanisms of secondary sulfanilamide resistance (SSR) development in patients with type 2 diabetes mellitus (DM). The work is aimed on studying the mechanisms of SSR development and on developing the methods of its correction. In the process of the work the clinical, laboratory, biochemical, immunogenetical, and instumental methods; and gamma-tomograph, and apparatus "Eksan G" were used by the author. The results of long sulfanilamide therapy in type 2 DM are estimated. Genetic determination and heterogeneity of SSR are determined. Indications to combined treatment of SSR are developed. The methods of SSR treatment with acarbose and carbamazepine are proposed for the first time. Data are included in medical practice of endocrinologists and also in lecture course of medical institutions.

Read more

Similar theses

0523U100041

Yuliya V. Buldygina

Graves' disease: pathogenetic aspects, clinico-morphological and immune factors, optimization of personalized treatment algorithms.

0521U102094

Cherska Mariia

Cardiocerebral disorders in patients with diabetes mellitus with cerebral atherosclerosis: features of relationships, factors of progression, diagnosis and ways of correction

0521U101828

Watseba Tamara Sergiyvna

Epidemiology of oncological diseases in patients with diabetes mellitus and the effect of antidiabetic medication on oncogenic markers.

0521U101330

Halyna P. Mykhalchyshyn

Pathophysiological mechanisms of the clinical progression variability and system of medical care for the patients with type 2 diabetes mellitus who also have non-alcoholic fatty liver disease.

0521U101295

Seliukova Nataliia Yuryevna

The reproductive system pathologies of offspring born to mothers with fetoplacental insufficiency: hormone depended mechanisms of developing and prophylaxis (experimental investigation).